Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens

Michael G. Giacomelli; Tadayuki Yoshitake; Lennart Husvogt; Lucas Cahill; Osman Ahsen; Hilde Vardeh; Yury Sheykin; Beverly E. Faulkner-Jones; Joachim Hornegger; Jeff Brooker; Alex Cable; James L. Connolly; James G. Fujimoto

doi:10.1117/12.2209241

14 March 2016 Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens

Michael G. Giacomelli, Tadayuki Yoshitake, Lennart Husvogt, Lucas Cahill, Osman Ahsen, Hilde Vardeh, Yury Sheykin, Beverly E. Faulkner-Jones, Joachim Hornegger, Jeff Brooker, Alex Cable, James L. Connolly, James G. Fujimoto

Author Affiliations +

Proceedings Volume 9712, Multiphoton Microscopy in the Biomedical Sciences XVI; 97121G (2016) https://doi.org/10.1117/12.2209241
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtual H&E images for real-time assessment. The imaging system and virtual H&E rendering algorithm are demonstrated by imaging unfixed human breast tissue in a clinical setting.

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Michael G. Giacomelli, Tadayuki Yoshitake, Lennart Husvogt, Lucas Cahill, Osman Ahsen, Hilde Vardeh, Yury Sheykin, Beverly E. Faulkner-Jones, Joachim Hornegger, Jeff Brooker, Alex Cable, James L. Connolly, and James G. Fujimoto "Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens", Proc. SPIE 9712, Multiphoton Microscopy in the Biomedical Sciences XVI, 97121G (14 March 2016); https://doi.org/10.1117/12.2209241

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