PbS/CdS QDs enabled SWIR imaging for lymphatic mapping and multiplexed lymph node imaging (Conference Presentation)

Xingjian Zhong; Amish Patel; Allison M. Dennis

doi:10.1117/12.2649410

17 March 2023 PbS/CdS QDs enabled SWIR imaging for lymphatic mapping and multiplexed lymph node imaging (Conference Presentation)

Xingjian Zhong, Amish Patel, Allison M. Dennis

Author Affiliations +

Proceedings Volume PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII; PC123950A (2023) https://doi.org/10.1117/12.2649410
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Short wave infrared (SWIR) imaging is an emerging imaging modality that utilizes the near infrared-II (NIR-II) biological window, spanning from 1000 nm to 1700 nm. In comparison with traditional NIR-I imaging, SWIR imaging advances with low autofluorescence and superior tissue penetration, leading to high signal-to-noise contrast. In this study, we synthesized multiple PbS/CdS core/shell QDs with distinctive emissions across the whole NIR-II window with high quantum yields and photostability. Empowered by the core/shell QDs, we performed detailed in vivo lymphatic system mapping and multiplexed lymph node imaging that were otherwise unachievable from established NIR-I imaging.

Conference Presentation

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Xingjian Zhong, Amish Patel, and Allison M. Dennis "PbS/CdS QDs enabled SWIR imaging for lymphatic mapping and multiplexed lymph node imaging (Conference Presentation)", Proc. SPIE PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII, PC123950A (17 March 2023); https://doi.org/10.1117/12.2649410

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KEYWORDS

Lymphatic system

Short wave infrared radiation

Multiplexing

Cadmium sulfide

Lead

Tissues

Scattering

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