Finite-difference modeling of laser ablation of tissue

Steven L. Jacques

doi:10.1117/12.147688

7 July 1993 Finite-difference modeling of laser ablation of tissue

Steven L. Jacques

Proceedings Volume 1882, Laser-Tissue Interaction IV; (1993) https://doi.org/10.1117/12.147688
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

Finite-difference modeling offers a flexible approach toward modeling tissue ablation. The model presented here considers optical penetration of the laser, thermal diffusion, water diffusion, surface evaporation, carbonization, and subsurface explosive vaporization. An example simulation considers near-infrared diode laser heating and ablation of a low- absorption nonscattering tissue which has been superficially stained with an absorbing dye (indocyanine green, ICG). Computer simulation illustrates 5 distinct phases of the process: (1) initial heating due to ICG absorption, (2) evaporation with surface clamped at 100 degree(s)C which desiccates surface layer, (3) heating of surface after desiccation has slowed evaporation, (4) rapid heating after onset of carbonization due to combination of desiccation and heating, and (5) subsurface explosive vaporization which removes a superficial tissue layer and exposes a fresh surface which repeats the above cycle.

Citation Download Citation

Steven L. Jacques "Finite-difference modeling of laser ablation of tissue", Proc. SPIE 1882, Laser-Tissue Interaction IV, (7 July 1993); https://doi.org/10.1117/12.147688

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