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Proceedings Article

Optical spectroscopy of benign and malignant breast tissues

[+] Author Affiliations
Yuanlong Yang, Alvin Katz, Robert R. Alfano

CUNY/City College (USA)

Edward J. Celmer, Margaret Zurawska-Szczepaniak

St. Vincent's Medical Ctr. of Richmond (USA)

Proc. SPIE 2679, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy, 51 (April 5, 1996); doi:10.1117/12.237597
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From Conference Volume 2679

  • Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy
  • Robert R. Alfano; Abraham Katzir
  • San Jose, CA | January 27, 1996

abstract

Fluorescence spectroscopy was applied to characterize normal, malignant and adipose breast tissues. Excitation, emission, and synchronized diffusive reflectance spectral scans were measured on over one hundred specimens for the purpose of developing an improved spectroscopic diagnostic technique. These techniques were able to successfully distinguish malignant tissue from adipose glandular fibrous and normal tissue. A sensitivity of 91% for fifty-six (56) malignant specimens with specificity of 91% for forty-six (46) benign tissue specimens has been achieved, using pathology as the golden standard.

© (1996) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Yuanlong Yang ; Alvin Katz ; Edward J. Celmer ; Margaret Zurawska-Szczepaniak and Robert R. Alfano
"Optical spectroscopy of benign and malignant breast tissues", Proc. SPIE 2679, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy, 51 (April 5, 1996); doi:10.1117/12.237597; http://dx.doi.org/10.1117/12.237597


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