Principles and techniques for measuring optical parameters of biotissue

Shusen Xie; Hui Li; Wei Zheng; Teck-Chee Chia; Sing Lee; Zhiwei Huang

doi:10.1117/12.251937

23 September 1996 Principles and techniques for measuring optical parameters of biotissue

Shusen Xie, Hui Li, Wei Zheng, Teck-Chee Chia, Sing Lee, Zhiwei Huang

Proceedings Volume 2887, Lasers in Medicine and Dentistry: Diagnostics and Treatment; (1996) https://doi.org/10.1117/12.251937
Event: Photonics China '96, 1996, Beijing, China

Abstract

In this paper, the principles of light propagation in tissue and techniques for measuring the optical parameters of tissues are briefly described. A new approach to measure optical parameters has been developed. We combine the solution of the diffusion theory with a result of Monte Carlo simulation to calculate the optical parameters of several mammalian tissue. This indirect approach might be used to determine the optical properties of human tissue. In addition, we also believe that the refractive index of bio- tissue is another important optical parameter in tissue optics. Recently, we have developed a new simple method based on total-internal-reflection to measure the refractive index of tissue. The main advantages of the method are its elimination of multiscattering effects, suitability to a small sample, and excellent accuracy of measurement. The refractive indices of skin from people of different age, sex and skin color in vivo was recently measured. We believe that it is the first set of data of index of refraction of human tissue in vivo.

Citation Download Citation

Shusen Xie, Hui Li, Wei Zheng, Teck-Chee Chia, Sing Lee, and Zhiwei Huang "Principles and techniques for measuring optical parameters of biotissue", Proc. SPIE 2887, Lasers in Medicine and Dentistry: Diagnostics and Treatment, (23 September 1996); https://doi.org/10.1117/12.251937

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