Development of silicone waveguides for use in a Raman spectroscopy-based sensor for general anesthetics

Julie R. Parnell; David Schutte; Paul Yager

doi:10.1117/12.275536

16 June 1997 Development of silicone waveguides for use in a Raman spectroscopy-based sensor for general anesthetics

Julie R. Parnell, David Schutte, Paul Yager

Proceedings Volume 2976, Biomedical Sensing, Imaging, and Tracking Technologies II; (1997) https://doi.org/10.1117/12.275536
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

A Raman spectroscopy-based sensor is being developed for general anesthetics or the small organics. The sensor uses a selectively-absorbent polymer to concentrate the analyte and thus produce a higher spectral signal intensity. This helps counteract the inherently low signal characteristic of Raman spectroscopic analyses. Waveguides have been fabricated from a commercially available methacrylate-functional silicone. Using diethoxyacetophenone photoinitiator and a silanizing agent to enhance adhesion, silicone waveguides have been photopolymerized onto fused silica substrates. Linear waveguides 200 micrometers wide and 240 micrometers thick exhibited attenuations on the order of 1.2 dB/cm, as determined by measurements of Raman silicone peak intensity down the length of the waveguide. Studies with liquid deuterochloroform in silicone oil yielded a detection limit of 0.092 MAC, where MAC, or minimum alveolar concentration, is a unit of measure for general anesthetics. Finally, partitioning of gaseous deuterochloroform into these waveguides produced a clearly discernible peak.

Citation Download Citation

Julie R. Parnell, David Schutte, and Paul Yager "Development of silicone waveguides for use in a Raman spectroscopy-based sensor for general anesthetics", Proc. SPIE 2976, Biomedical Sensing, Imaging, and Tracking Technologies II, (16 June 1997); https://doi.org/10.1117/12.275536

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