Optical imaging reconstruction using the average value as the reference

Yukio Ueda; Kazuyoshi Ohta; Motoki Oda; Mitsuharu Miwa; Yutaka Yamashita; Yutaka Tsuchiya

doi:10.1117/12.280227

18 August 1997 Optical imaging reconstruction using the average value as the reference

Yukio Ueda, Kazuyoshi Ohta, Motoki Oda, Mitsuharu Miwa, Yutaka Yamashita, Yutaka Tsuchiya

Proceedings Volume 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II; (1997) https://doi.org/10.1117/12.280227
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

We propose a new algorithm for optical computed tomography (CT) to quantify the absorptive substances in highly scattering media such as human tissues. Our algorithm uses the uniform medium in which scattering and absorption coefficients are equivalent to the average coefficients of the actual object to be measured. In other words, we use an imaginary reference. When the weight function and re-emissions are measurable or can be calculated for the imaginary reference, we can describe the inside structure of the non-uniform object using the deviation of the absorption coefficient from the average value. Since it is difficult to prepare a phantom of which exterior shape and inside structure are identical to that of the real objects, conventional methods cannot be free from the significant errors. The averages of the absorption and scattering coefficients are obtained by measurements such as time-resolved spectroscopy. The weight function and re- missions can be calculated using the average values by a Monte Carlo simulation or a finite difference method. The absolute absorption coefficient is obtained as the sum of the average and the deviation. The validity of our algorithm was confirmed by measuring a tissue-like phantom which contains three different absorbers. We evaluated reconstructed images and confirmed that the new method gives better accuracy in the quantitation of the concentration of absorbing substance and a smaller image distortion. Our results have significant implications for optical CT which quantifies the concentration of absorbing substances accurately without measuring the reference phantom.

Citation Download Citation

Yukio Ueda, Kazuyoshi Ohta, Motoki Oda, Mitsuharu Miwa, Yutaka Yamashita, and Yutaka Tsuchiya "Optical imaging reconstruction using the average value as the reference", Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); https://doi.org/10.1117/12.280227

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