Depolarization effects accompanying the coherent light multiple scattering by optically inhomogeneous tissues are studied for the certain cases of the light-tissue interaction. Correlation between polarization states of the scattered light fields (speckle patterns) for different stages of the transition from multiple scattering mode to the single scattering one is experimentally analyzed for the case of human sclera enlightenment process. This process can be induced by the application of the special chemical agents (e.g., Trazograph solution). Reversibility of the enlightenment is demonstrated by measuring mean intensities of the scattered light for different polarization states. Some possibilities of the usage of this approach for turbid media structure visualization are discussed.© (1997) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.