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Proceedings Article

Dielectrophoresis of micro/nano particles using curved microelectrodes

[+] Author Affiliations
Khashayar Khoshmanesh, Saeid Nahavandi

Deakin Univ. (Australia)

Francisco J. Tovar-Lopez, Aminuddin A. Kayani, Adam F. Chrimes, Arnan Mitchell, Kourosh Kalantar-zadeh

RMIT Univ. (Australia)

Sara Baratchi

Monash Univ. (Australia)

Chen Zhang

Univ. of South Australia (Australia)

Donald Wlodkowic

Univ. of Auckland (New Zealand)

Proc. SPIE 8204, Smart Nano-Micro Materials and Devices, 82040G (December 23, 2011); doi:10.1117/12.903183
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From Conference Volume 8204

  • Smart Nano-Micro Materials and Devices
  • Saulius Juodkazis; Min Gu
  • Melbourne, Australia | December 04, 2011

abstract

Dielectrophoresis, the induced motion of polarisable particles in non-homogenous electric field, has been proven as a versatile mechanism to transport, immobilise, sort and characterise micro/nano scale particle in microfluidic platforms. The performance of dielectrophoretic (DEP) systems depend on two parameters: the configuration of microelectrodes designed to produce the DEP force and the operating strategies devised to employ this force in such processes. This work summarises the unique features of curved microelectrodes for the DEP manipulation of target particles in microfluidic systems. The curved microelectrodes demonstrate exceptional capabilities including (i) creating strong electric fields over a large portion of their structure, (ii) minimising electro-thermal vortices and undesired disturbances at their tips, (iii) covering the entire width of the microchannel influencing all passing particles, and (iv) providing a large trapping area at their entrance region, as evidenced by extensive numerical and experimental analyses. These microelectrodes have been successfully applied for a variety of engineering and biomedical applications including (i) sorting and trapping model polystyrene particles based on their dimensions, (ii) patterning carbon nanotubes to trap low-conductive particles, (iii) sorting live and dead cells based on their dielectric properties, (iv) real-time analysis of drug-induced cell death, and (v) interfacing tumour cells with environmental scanning electron microscopy to study their morphological properties. The DEP systems based on curved microelectrodes have a great potential to be integrated with the future lab-on-achip systems.

© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

Khashayar Khoshmanesh ; Francisco J. Tovar-Lopez ; Sara Baratchi ; Chen Zhang ; Aminuddin A. Kayani, et al.
"Dielectrophoresis of micro/nano particles using curved microelectrodes", Proc. SPIE 8204, Smart Nano-Micro Materials and Devices, 82040G (December 23, 2011); doi:10.1117/12.903183; http://dx.doi.org/10.1117/12.903183


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