Field-based multiplex and quantitative assay platforms for diagnostics

Srivatsa Venkatasubbarao; C. Edward Dixon; Russell Chipman; Axel Scherer; Manal Beshay; Lothar U. Kempen; Jai Ganesh Chandra Sekhar; Hong Yan; Ava Puccio; David Okonkwo; Stephen McClain; Noah Gilbert; Saurabh Vyawahare

doi:10.1117/12.886661

17 May 2011 Field-based multiplex and quantitative assay platforms for diagnostics

Srivatsa Venkatasubbarao, C. Edward Dixon, Russell Chipman, Axel Scherer, Manal Beshay, Lothar U. Kempen, Jai Ganesh Chandra Sekhar, Hong Yan, Ava Puccio, David Okonkwo, Stephen McClain, Noah Gilbert, Saurabh Vyawahare

Author Affiliations +

Proceedings Volume 8029, Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring; and Biometric Technology for Human Identification VIII; 80290P (2011) https://doi.org/10.1117/12.886661
Event: SPIE Defense, Security, and Sensing, 2011, Orlando, Florida, United States

Abstract

The U.S. military has a continued interest in the development of handheld, field-usable sensors and test kits for a variety of diagnostic applications, such as traumatic brain injury (TBI) and infectious diseases. Field-use presents unique challenges for biosensor design, both for the readout unit and for the biological assay platform. We have developed robust biosensor devices that offer ultra-high sensitivity and also meet field-use needs. The systems under development include a multiplexed quantitative lateral flow test strip for TBI diagnostics, a field test kit for the diagnosis of pathogens endemic to the Middle East, and a microfluidic assay platform with a label-free reader for performing complex biological automated assays in the field.

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Srivatsa Venkatasubbarao, C. Edward Dixon, Russell Chipman, Axel Scherer, Manal Beshay, Lothar U. Kempen, Jai Ganesh Chandra Sekhar, Hong Yan, Ava Puccio, David Okonkwo, Stephen McClain, Noah Gilbert, and Saurabh Vyawahare "Field-based multiplex and quantitative assay platforms for diagnostics", Proc. SPIE 8029, Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring; and Biometric Technology for Human Identification VIII, 80290P (17 May 2011); https://doi.org/10.1117/12.886661

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