Full Content is available to subscribers

Subscribe/Learn More  >
Proceedings Article

Multimode spectroscopy for the in vivo assessment of post-inflammatory pigmentation: preliminary observations

[+] Author Affiliations
Jianhua Zhao, Haishan Zeng, David I. McLean, Harvey Lui

BC Cancer Research Ctr. (Canada) and Univ. of British Columbia (Canada) and Vancouver Coastal Health Research Institute (Canada)

Hana Alkhayat, Ahmad Al Robaee

Univ. of British Columbia (Canada) and Vancouver Coastal Health Research Institute (Canada)

Proc. SPIE 6078, Photonic Therapeutics and Diagnostics II, 607809 (February 22, 2006); doi:10.1117/12.650200
Text Size: A A A
From Conference Volume 6078

  • Photonic Therapeutics and Diagnostics II
  • Nikiforos Kollias; Haishan Zeng; Bernard Choi; Reza S. Malek; Brian J. Wong; Justus F. R. Ilgner; Eugene A. Trowers; Werner T. de Riese; Henry Hirschberg; Steen J. Madsen; Michael D. Lucroy; Lloyd P. Tate; Kenton W. Gregory; Guillermo J. Tearney
  • San Jose, CA | January 21, 2006

abstract

Although post-inflammatory pigmentation (PIH) is a common acquired skin disorder, however, its mechanism still remains unclear. In this paper, multimode optical spectroscopic techniques including diffuse reflectance spectroscopy, fluorescence spectroscopy and Raman spectroscopy have been used to probe the morphologic and biochemical changes associated with PIH. Both pigmented skin and the adjacent normal skin were measured for paired analysis. Distinctive spectral features were observed which may provide the potentials for identifying the mechanism of PIH. The diffuse reflectance spectrum was also converted into the CIE standard L*a*b* color system. The melanin and the hemoglobin content in the PIH were quantitatively derived from the diffusive reflectance spectrum using the Stamatas-Kollias algorithm. It was found that PIH always has a lower value in L* and more melanin and hemoglobin content which is consistent with clinical appearance of dark skin as perceived by the human eye.

© (2006) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Jianhua Zhao ; Hana Alkhayat ; Ahmad Al Robaee ; Haishan Zeng ; David I. McLean, et al.
"Multimode spectroscopy for the in vivo assessment of post-inflammatory pigmentation: preliminary observations", Proc. SPIE 6078, Photonic Therapeutics and Diagnostics II, 607809 (February 22, 2006); doi:10.1117/12.650200; http://dx.doi.org/10.1117/12.650200


Access This Proceeding
Sign in or Create a personal account to Buy this proceeding ($15 for members, $18 for non-members).

Figures

Tables

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement


 

  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Proceeding
Sign in or Create a personal account to Buy this proceeding ($15 for members, $18 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.