Molecular imaging with surface-enhanced CARS on nanostructures

Christian Steuwe; Clemens F. Kaminski; Jeremy J. Baumberg; Sumeet Mahajan

doi:10.1117/12.908272

6 February 2012 Molecular imaging with surface-enhanced CARS on nanostructures

Christian Steuwe, Clemens F. Kaminski, Jeremy J. Baumberg, Sumeet Mahajan

Proceedings Volume 8234, Plasmonics in Biology and Medicine IX; 82340E (2012) https://doi.org/10.1117/12.908272
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Strongly localized electromagnetic fields in the vicinity of nanoparticles and nanogaps greatly enhance spectroscopic signals near them such as in surface-enhanced Raman spectroscopy (SERS). In this work we combine this plasmonic surface enhancement with coherent anti-Stokes Raman spectroscopy (CARS) on reproducible nanostructured surfaces. Surface-enhanced CARS (SECARS) gives rise to very strong enhancements and we find that an enhancement of ~10⁵ can be obtained over standard CARS. Using our nanostructured surfaces, we demonstrate strong correlation between plasmon resonances and surface-enhanced CARS intensities. Furthermore, fast imaging of molecular monolayers is performed. Our work paves the way for reliable single molecule Raman spectroscopy and fast molecular imaging on plasmonic surfaces.

Citation Download Citation

Christian Steuwe, Clemens F. Kaminski, Jeremy J. Baumberg, and Sumeet Mahajan "Molecular imaging with surface-enhanced CARS on nanostructures", Proc. SPIE 8234, Plasmonics in Biology and Medicine IX, 82340E (6 February 2012); https://doi.org/10.1117/12.908272

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