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Proceedings Article

Bio optofluidics cell sorter: cell-BOCS concept and applications

[+] Author Affiliations
Tue Roth, Jesper Glückstad

Technical Univ. of Denmark (Denmark)

Proc. SPIE 8274, Complex Light and Optical Forces VI, 82740J (February 9, 2012); doi:10.1117/12.909783
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From Conference Volume 8274

  • Complex Light and Optical Forces VI
  • Enrique J. Galvez; David L. Andrews; Jesper Glückstad; Marat S. Soskin
  • San Francisco, California, USA | January 21, 2012

abstract

The cell-BOCS is a novel microfluidics based cell-sorting instrument utilizing next generation optical trapping technology developed at the Technical University of Denmark. It is targeted emerging bio-medical research and diagnostics markets where it for certain applications offers a number of advantages over conventional fluorescence activated cell-sorting (FACSTM) technology. Advantages include gentle handling of cells, sterile sorting, easy operation, small footprint and lower cost allowing out-of-core-facility use. Application examples are found within sorting of fragile transfected cells, high value samples and primary cell lines, where traditional FACS technology has limited application due to it's droplet-based approach to cell-sorting. In the diagnostics field, in particular applying the cell-BOCS for isolating pure populations of circulating tumor cells is an area that has generated a lot of interest.

© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

Tue Roth and Jesper Glückstad
"Bio optofluidics cell sorter: cell-BOCS concept and applications", Proc. SPIE 8274, Complex Light and Optical Forces VI, 82740J (February 9, 2012); doi:10.1117/12.909783; http://dx.doi.org/10.1117/12.909783


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