Paper
23 March 2007 Obstructive sleep apnea screening by NIRS imaging
Feraydune Kashefi, Donald E. Watenpaugh, Hanli Liu
Author Affiliations +
Abstract
This study aimed at determining cerebral hemodynamic parameters in human subjects during breath holding using near infrared spectroscopy (NIRS). Breath holding serves as a method of simulation OSA (Obstructive Sleep Apnea). Data was acquired non-invasively from 40 subjects, twenty OSA sufferers (10 females, 10 males, age 20-70 years), and twenty normal volunteers (10 females, 10 males, age 20-65 years). Measurements were conducted using a LED Imager (LEDI) during breath holding. In comparing OSA subjects with controls during breath holding, a consistent increase or even a decrease in oxy- ([O2Hb]), deoxy- ([HHb]), total hemoglobin ([tHb]) concentrations, and tissue hemoglobin oxygen saturation (SO2) in the regional brain tissue were observed. The LEDI probe consists of 4 sources and 10 detectors serving as 4 sets of 1 source and 4 detectors each. A three wavelength (730, 805, and 850 nm) LED was used and the wavelengths were switched sequentially. The distance between sources and the source-detector separation were 2.5 cm. Data acquisition consisted of three segments, baseline for one minute, followed by a period of breath holding, and then 2 minutes of recovery time. The duration of the breath holding was subject-dependent. Our investigation proves that NIR spectroscopy could be used as a tool for detecting cerebral hemodynamics and also serves as a method of screening patients with OSA.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Feraydune Kashefi, Donald E. Watenpaugh, and Hanli Liu "Obstructive sleep apnea screening by NIRS imaging", Proc. SPIE 6424, Photonic Therapeutics and Diagnostics III, 64242H (23 March 2007); https://doi.org/10.1117/12.702239
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KEYWORDS
Near infrared spectroscopy

Brain

Control systems

Hemodynamics

Oxygen

Sensors

Tissues

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