Application of adaptive optics: optical coherence tomography for in vivo imaging of microscopic structures in the retina and optic nerve head

Robert J. Zawadzki; Yan Zhang II; Steven M. Jones; Stacey S. Choi; Barry Cense; Diana Chen; Alfred R. Fuller; Donald T. Miller; Scot S. Olivier; John S. Werner

doi:10.1117/12.701512

5 March 2007 Application of adaptive optics: optical coherence tomography for in vivo imaging of microscopic structures in the retina and optic nerve head

Robert J. Zawadzki, Yan Zhang II, Steven M. Jones, Stacey S. Choi, Barry Cense, Diana Chen, Alfred R. Fuller, Donald T. Miller, Scot S. Olivier, John S. Werner

Author Affiliations +

Proceedings Volume 6426, Ophthalmic Technologies XVII; 64261O (2007) https://doi.org/10.1117/12.701512
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

Two deformable mirrors (2DM) were used in an adaptive optics - optical coherence tomography (AO-OCT) system to image in vivo microscopic retinal structures of healthy and diseased retinas. As a result, multiple morphological structures not previously seen in vivo have been visualized. Among those presented are three-dimensional representations of the fovea and optic nerve head (ONH), revealing cellular structures and micro-vasculature. Drusen in macular degeneration and photoreceptor dystrophies are also presented. Different methods for displaying volumetric AO-OCT data to facilitate visualization of certain morphological details are compared.

Citation Download Citation

Robert J. Zawadzki, Yan Zhang II, Steven M. Jones, Stacey S. Choi, Barry Cense, Diana Chen, Alfred R. Fuller, Donald T. Miller, Scot S. Olivier, and John S. Werner "Application of adaptive optics: optical coherence tomography for in vivo imaging of microscopic structures in the retina and optic nerve head", Proc. SPIE 6426, Ophthalmic Technologies XVII, 64261O (5 March 2007); https://doi.org/10.1117/12.701512

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available