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Proceedings Article

Fluorescence optical tomography with a priori information

[+] Author Affiliations
Murat Guven, Birsen Yazici

Rensselaer Polytechnic Institute

Vasilis Ntziachristos

Harvard Medical School

Proc. SPIE 6431, Multimodal Biomedical Imaging II, 643107 (February 14, 2007); doi:10.1117/12.715073
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From Conference Volume 6431

  • Multimodal Biomedical Imaging II
  • Fred S. Azar
  • San Jose, CA | January 20, 2007

abstract

In this work, we discuss the incorporation of a priori information into the inverse problem formulation for fluorescence optical tomography. In this respect, we first formulate the inverse problem in the optimization framework which allows the incorporation of a priori information about the solution and its gradient. Then, we consider the variational problem, which is equivalent to the optimization problem and prove the existence and uniqueness of the solution. Finally, we discuss the design of the functions that incorporate the a priori information into the inverse problem formulation and present a model problem to illustrate the design procedure.

© (2007) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Murat Guven ; Birsen Yazici and Vasilis Ntziachristos
"Fluorescence optical tomography with a priori information", Proc. SPIE 6431, Multimodal Biomedical Imaging II, 643107 (February 14, 2007); doi:10.1117/12.715073; http://dx.doi.org/10.1117/12.715073


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