In-vivo characterization of a microdialysis-based pH sensor

F. Baldini; F. Feichtner; A. Giannetti; G. Gori; A. A. Mencaglia; V. Pavoni; A. M. Perna; C. Trono

doi:10.1117/12.738605

2 July 2007 In-vivo characterization of a microdialysis-based pH sensor

F. Baldini, F. Feichtner, A. Giannetti, G. Gori, A. A. Mencaglia, V. Pavoni, A. M. Perna, C. Trono

Proceedings Volume 6619, Third European Workshop on Optical Fibre Sensors; 661922 (2007) https://doi.org/10.1117/12.738605
Event: Third European Workshop on Optical Fibre Sensors, 2007, Napoli, Italy

Abstract

A pH sensor based on optical fibres was developed. The analysed sample is the interstitial fluid drawn from the adipose tissue by means of a microdialysis catheter. The pH sensing layer is constituted by a pH indicator, phenol red, directly immobilised onto the internal wall of a glass capillary. The interrogation of the glass capillary is performed by an optoelectronic unit, developed in our laboratory, which makes use of a light emitting diode at 590 nm as source and a photodiode as detector. A suitable animal model was developed and in-vivo tests on pigs were carried out.

Citation Download Citation

F. Baldini, F. Feichtner, A. Giannetti, G. Gori, A. A. Mencaglia, V. Pavoni, A. M. Perna, and C. Trono "In-vivo characterization of a microdialysis-based pH sensor", Proc. SPIE 6619, Third European Workshop on Optical Fibre Sensors, 661922 (2 July 2007); https://doi.org/10.1117/12.738605

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