Micro-optics for optical trapping in microfluidics

Fabrice Merenda; Johann Rohner; Elodie Lamothe; Pedro Pascoal; Jean-Marc Fournier; René-Paul Salathé

doi:10.1117/12.738268

5 September 2007 Micro-optics for optical trapping in microfluidics

Fabrice Merenda, Johann Rohner, Elodie Lamothe, Pedro Pascoal, Jean-Marc Fournier, René-Paul Salathé

Proceedings Volume 6644, Optical Trapping and Optical Micromanipulation IV; 66440P (2007) https://doi.org/10.1117/12.738268
Event: NanoScience + Engineering, 2007, San Diego, California, United States

Abstract

Micro-optical components offer several possibilities for creating large matrices of optical traps, either when working on inverted microscopes, or by directly integrating miniaturized optical components at the level of a micro-fluidic chip. In this article we focus on two particular configurations, both allowing to generate large arrays of 3D optical traps. The first configuration takes advantage of an array of refractive microlenses to generate multiple optical tweezers within the focal plane of a high-NA microscope objective. The second configuration relies on an array of focusing high-NA micromirrors which are directly integrated at the level of a micro-fluidic chip. We also present measurements of the maximal optical trapping forces that can be reached with several types of cells commonly employed in biology and biotechnology, and demonstrate that these forces are essentially related to the bulk refractive index of the cells.

Citation Download Citation

Fabrice Merenda, Johann Rohner, Elodie Lamothe, Pedro Pascoal, Jean-Marc Fournier, and René-Paul Salathé "Micro-optics for optical trapping in microfluidics", Proc. SPIE 6644, Optical Trapping and Optical Micromanipulation IV, 66440P (5 September 2007); https://doi.org/10.1117/12.738268

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