Optical tweezers are widely used for manipulating microscopic objects. Compared to other contact type microscopic manipulators such as micro-grippers that exhibit firm gripping, optical tweezers inherently possess loose gripping. For example, if a user tries to move target objects too fast such that the drag force of the viscous fluid exceeds the trapping force, target objects will escape from the effective trapping region. When this happens in a standard user interface environment with only video feedback, the user would sense this with a visual cue and slow down or slightly reverse the movement of the trap. In this study we enrich the user interface by adding a haptic cue that is a sense of forces and torques so that the user will sense the drag force and torque that is proportional to the gap distance and angle between the line trap and the nanowire. We present some preliminary results of putting haptic cue for manipulating nanowires.© (2007) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.