We propose and demonstrate a new type of a photonic crystal nanolaser integrated into a microfluidic chip, which is fabricated by multilayer soft lithography. Experimentally, continuous-wave operation of the lasing action has been observed owing to efficient water-cooling. Characteristics of wavelength tuning by the fluid are investigated using both theory and experiment. In addition, we propose that dynamic modulation of far-field radiation pattern can be achieved by introducing a bottom reflector and by flowing the fluid on it. Especially, by choosing effective one-wavelength distance between the reflector and the cavity, efficient unidirectional emission can be obtained.© (2007) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.