Homodyne 2lambda and 2f phase-modulation system for brain oxymetry

Svetlana A. Tatarkova; Eduardo Gudis; Aaron R. Castillo; Lisa Dung Ho; William J. Barger; Britton Chance

doi:10.1117/12.341412

4 March 1999 Homodyne 2λ and 2f phase-modulation system for brain oxymetry

Svetlana A. Tatarkova, Eduardo Gudis, Aaron R. Castillo, Lisa Dung Ho, William J. Barger, Britton Chance

Proceedings Volume 3726, Saratov Fall Meeting '98: Light Scattering Technologies for Mechanics, Biomedicine, and Material Science; (1999) https://doi.org/10.1117/12.341412
Event: Saratov Fall Meeting '98: Light Scattering Technologies for Mechanics, Biomedicine, and Material Science, 1998, Saratov, Russian Federation

Abstract

Recently noninvasive near-infrared techniques have been developed to determine the concentrations of oxygenated and deoxygenated haemoglobin in the living biological tissue. New dual wavelength and dual frequency instrument with the phase modulation of the laser light has been designed and built for studies the oxygen dynamics in human tissue. This instrumentation is low cost and acquire data in widely different frequency and wavelength regions. We have presented the comprehensive calibration procedures applied to the instrument and demonstrated the appropriate working range of the measuring optical parameters. Also has been calculated the haemoglobin saturation of the tissue-like phantom using the results of the photon-diffusion theory for infinitive geometry approximation. Our results have shown the good accuracy and sensitivity in the different experimental conditions suitable for clinic researches.

Citation Download Citation

Svetlana A. Tatarkova, Eduardo Gudis, Aaron R. Castillo, Lisa Dung Ho, William J. Barger, and Britton Chance "Homodyne 2λ and 2f phase-modulation system for brain oxymetry", Proc. SPIE 3726, Saratov Fall Meeting '98: Light Scattering Technologies for Mechanics, Biomedicine, and Material Science, (4 March 1999); https://doi.org/10.1117/12.341412

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