Paper
1 July 2003 Midinfrared laser absorption spectroscopy in coiled hollow optical waveguides
Gregory J. Fetzer, Anthony S. Pittner, Philip E. Silkoff
Author Affiliations +
Abstract
A new nitric oxide (NO) sensor is intended for use in assessment of airway inflammation with applications in asthma diagnosis and management as well as in other health care applications involving inflammation in the gastrointestinal tract and the urogenital organs. The sensor was designed to measure trace quantities of NO in air using the combination of hollow optical waveguides and quantum cascade lasers. The primary application intended is analysis of exhaled breath. The unique marriage of the components and the novel design provides for rapid response to concentration changes while maintaining sensitive measurement capabilities. We achieved a lower detectable limit of 58.8 ppb of NO in N2 with a 0-90% response time of 0.48 s. The QC laser was operated at room temperature in pulsed current mode near 5.4μm. The hollow waveguide used to make these measurements was 9m in length and the inside diameter was 1000μm. The waveguide was coiled with a 15cm radius of curvature and perforated on the interior walls of the coils to allow gas to flow into and out of the waveguide. The sensor can easily be converted to measure other gases in the midinfrared by selecting a QC laser whose output is coincident with the absorption line of interest.
© (2003) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Gregory J. Fetzer, Anthony S. Pittner, and Philip E. Silkoff "Midinfrared laser absorption spectroscopy in coiled hollow optical waveguides", Proc. SPIE 4957, Optical Fibers and Sensors for Medical Applications III, (1 July 2003); https://doi.org/10.1117/12.485398
Lens.org Logo
CITATIONS
Cited by 5 scholarly publications and 2 patents.
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Waveguides

Absorption

Modulation

Inflammation

Quantum cascade lasers

Sensors

Digital signal processing

Back to Top