In vivo retinal blood flow measurement by Fourier domain Doppler optical coherence tomography

Yimin Wang; Ou Tan; David Huang M.D.

doi:10.1117/12.765320

5 March 2008 In vivo retinal blood flow measurement by Fourier domain Doppler optical coherence tomography

Yimin Wang, Ou Tan, David Huang M.D.

Proceedings Volume 6847, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII; 68470G (2008) https://doi.org/10.1117/12.765320
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

The measurement of ocular blood flow is important in studying the pathophysiology and treatment of several leading causes of blindness. We present a method for in vivo human retinal flow measurement using Fourier domain optical coherence tomography. A double circular scanning pattern was used to scan the blood vessels around the optic nerve head 8 times over 2 seconds. The venous flow totaled 36.13 μl/min in the right eye of a volunteer. The flow difference was observed before and after breath holding. The fast flow measurement method did not require any assumption on the flow profile over time or space.

Citation Download Citation

Yimin Wang, Ou Tan, and David Huang M.D. "In vivo retinal blood flow measurement by Fourier domain Doppler optical coherence tomography", Proc. SPIE 6847, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII, 68470G (5 March 2008); https://doi.org/10.1117/12.765320

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