Flow measurement by using the signal decrease of moving scatterers in spatially encoded Fourier domain optical coherence tomography

Julia Walther; Edmund Koch

doi:10.1117/12.808737

20 February 2009 Flow measurement by using the signal decrease of moving scatterers in spatially encoded Fourier domain optical coherence tomography

Julia Walther, Edmund Koch

Author Affiliations +

Proceedings Volume 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII; 71681S (2009) https://doi.org/10.1117/12.808737
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Blood flow measurement with spectrometer-based Fourier domain optical coherence tomography (FD-OCT) is limited by the motion-induced signal fading and the resulting reduction of flow sensitivity. Therefore, we have numerically simulated the signal power decrease of an obliquely moved scattering layer as a function of the absolute sample velocity composed of an axial and transverse component. In contrast to the prevalent expectance, the resulting signal damping is not only the sum of axial and transverse effect. In this study, we take advantage of the signal decay and present the feasibility to quantify high flow velocities at which the standard Doppler OCT does not work any longer. For the validation of our approach, a flow phantom model consisting of a 1%-Intralipid solution and a 320 μm glass capillary was used. With this phantom study, depth-resolved flow was visualized and the quantitative velocities were extracted from the OCT images without phase information.

Citation Download Citation

Julia Walther and Edmund Koch "Flow measurement by using the signal decrease of moving scatterers in spatially encoded Fourier domain optical coherence tomography", Proc. SPIE 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII, 71681S (20 February 2009); https://doi.org/10.1117/12.808737

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