JPEG 2000 image compression allows many formatting alternatives, but users frequently have insufficient knowledge or experience to direct the choice. At compression time many of these options may seem approximately equal, but during exploitation the file structure differences can have a huge impact on access speed. This is particularly true for very large images such as those regularly used in remote sensing and many defense systems. This paper examines the impacts of JPEG 2000 options such as tiling, tile-parts, precincts, and packet ordering on large single band images, particularly in relationship to random access speed.© (2008) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.