Clinical results with acridine orange using a novel confocal laparoscope

Anthony A. Tanbakuchi; Andrew R. Rouse; Kenneth D. Hatch M.D.; Arthur F. Gmitro

doi:10.1117/12.809540

2 March 2009 Clinical results with acridine orange using a novel confocal laparoscope

Anthony A. Tanbakuchi, Andrew R. Rouse, Kenneth D. Hatch M.D., Arthur F. Gmitro

Proceedings Volume 7172, Endoscopic Microscopy IV; 71720H (2009) https://doi.org/10.1117/12.809540
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

We previously reported on the development of a multi-spectral confocal laparoscope for clinical imaging. In this paper we present current results using the system to image ovaries with a new laparoscope design using the contrast agent acridine orange. This new laparoscope integrates computer controlled systems for focus, depth scans, and localized contrast agent delivery. Precise axial position control is accomplished with tiny stepper motors integrated inside the laparoscope handle. Ergonomic handle controls allow for data acquisition, deliver of contrast agents, and adjustment of imaging depth during procedures by the surgeon. We have approval to use acridine orange in our clinical trials to image ovaries in vivo during oophorectomies. We present in vivo results using both acridine orange and fluorescein as the topically administered contrast agent.

Citation Download Citation

Anthony A. Tanbakuchi, Andrew R. Rouse, Kenneth D. Hatch M.D., and Arthur F. Gmitro "Clinical results with acridine orange using a novel confocal laparoscope", Proc. SPIE 7172, Endoscopic Microscopy IV, 71720H (2 March 2009); https://doi.org/10.1117/12.809540

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