Clinical utility of magnetic resonance thermal imaging (MRTI) for realtime guidance of deep hyperthermia

P. R. Stauffer; Oana I. Craciunescu; P. F. Maccarini; Cory Wyatt; K. Arunachalam; O. Arabe; V. Stakhursky; B. Soher; J. R. MacFall; Z. Li; William T. Joines; S. Rangarao; K. S. Cheng; S. K. Das; Carlos D. Martins; Cecil Charles; Mark W. Dewhirst; T. Wong; E. Jones M.D.; Z. Vujaskovic M.D.

doi:10.1117/12.812188

25 February 2009 Clinical utility of magnetic resonance thermal imaging (MRTI) for realtime guidance of deep hyperthermia

P. R. Stauffer, Oana I. Craciunescu, P. F. Maccarini, Cory Wyatt, K. Arunachalam, O. Arabe, V. Stakhursky, B. Soher, J. R. MacFall, Z. Li, William T. Joines, S. Rangarao, K. S. Cheng, S. K. Das, Carlos D. Martins, Cecil Charles, Mark W. Dewhirst, T. Wong, E. Jones M.D., Z. Vujaskovic M.D.

Author Affiliations +

Proceedings Volume 7181, Energy-based Treatment of Tissue and Assessment V; 71810I (2009) https://doi.org/10.1117/12.812188
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

A critical need has emerged for volumetric thermometry to visualize 3D temperature distributions in real time during deep hyperthermia treatments used as an adjuvant to radiation or chemotherapy for cancer. For the current effort, magnetic resonance thermal imaging (MRTI) is used to measure 2D temperature rise distributions in four cross sections of large extremity soft tissue sarcomas during hyperthermia treatments. Novel hardware and software techniques are described which improve the signal to noise ratio of MR images, minimize motion artifact from circulating coupling fluids, and provide accurate high resolution volumetric thermal dosimetry. For the first 10 extremity sarcoma patients, the mean difference between MRTI region of interest and adjacent interstitial point measurements during the period of steady state temperature was 0.85°C. With 1min temporal resolution of measurements in four image planes, this noninvasive MRTI approach has demonstrated its utility for accurate monitoring and realtime steering of heat into tumors at depth in the body.

Citation Download Citation

P. R. Stauffer, Oana I. Craciunescu, P. F. Maccarini, Cory Wyatt, K. Arunachalam, O. Arabe, V. Stakhursky, B. Soher, J. R. MacFall, Z. Li, William T. Joines, S. Rangarao, K. S. Cheng, S. K. Das, Carlos D. Martins, Cecil Charles, Mark W. Dewhirst, T. Wong, E. Jones M.D., and Z. Vujaskovic M.D. "Clinical utility of magnetic resonance thermal imaging (MRTI) for realtime guidance of deep hyperthermia", Proc. SPIE 7181, Energy-based Treatment of Tissue and Assessment V, 71810I (25 February 2009); https://doi.org/10.1117/12.812188

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available