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Proceedings Article

Applications of fluorescence spectroscopy to problems of food safety: detection of fecal contamination and of the presence of central nervous system tissue and diagnosis of neurological disease

[+] Author Affiliations
Ramkrishna Adhikary, Sayantan Bose, Jacob W. Petrich

Iowa State Univ. (USA)

Thomas A. Casey

National Animal Disease Ctr., USDA (USA)

Al Gapsch

TECHnical SOLutions Group, Inc. (USA)

Mark A. Rasmussen

Ctr. for Veterinary Medicine, U.S. Food and Drug Administration (USA)

Proc. SPIE 7576, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II, 757617 (February 16, 2010); doi:10.1117/12.841829
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From Conference Volume 7576

  • Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II
  • Samuel Achilefu; Ramesh Raghavachari
  • San Francisco, California | January 23, 2010

abstract

Applications of fluorescence spectroscopy that enable the real-time or rapid detection of fecal contamination on beef carcasses and the presence of central nervous system tissue in meat products are discussed. The former is achieved by employing spectroscopic signatures of chlorophyll metabolites; the latter, by exploiting the characteristic structure and intensity of lipofuscin in central nervous system tissue. The success of these techniques has led us to investigate the possibility of diagnosing scrapie in sheep by obtaining fluorescence spectra of the retina. Crucial to this diagnosis is the ability to obtain baseline correlations of lipofuscin fluorescence with age. A murine model was employed as a proof of principle of this correlation.

© (2010) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Ramkrishna Adhikary ; Sayantan Bose ; Thomas A. Casey ; Al Gapsch ; Mark A. Rasmussen, et al.
"Applications of fluorescence spectroscopy to problems of food safety: detection of fecal contamination and of the presence of central nervous system tissue and diagnosis of neurological disease", Proc. SPIE 7576, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II, 757617 (February 16, 2010); doi:10.1117/12.841829; http://dx.doi.org/10.1117/12.841829


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