Gabor domain optical coherence microscopy

Jannick P. Rolland; Panomsak Meemon; Supraja Murali; Ilhan Kaya; Nicolene Papp; Kevin P. Thompson; Kye-Sung Lee

doi:10.1117/12.831846

13 July 2009 Gabor domain optical coherence microscopy

Jannick P. Rolland, Panomsak Meemon, Supraja Murali, Ilhan Kaya, Nicolene Papp, Kevin P. Thompson, Kye-Sung Lee

Proceedings Volume 7372, Optical Coherence Tomography and Coherence Techniques IV; 73721K (2009) https://doi.org/10.1117/12.831846
Event: European Conferences on Biomedical Optics, 2009, Munich, Germany

Abstract

In this paper, we present a developing technology targeted at clinical imaging, Gabor Domain Optical Coherence Microscopy (GD-OCM), which combines the high resolution imaging of optical coherence microscopy (OCM), high imaging speed of Fourier domain optical coherence tomography (FD-OCT), and invariant lateral resolution of our custom designed dynamic focusing objective. A high lateral resolution optical design of a dynamic-focusing optical probe with no moving parts, which provides an invariant resolution of currently < 3 μm across a 2mm full-field of view and 2mm imaging depth, is presented. Furthermore, an acquisition scheme (using the probe) that is capable of performing automatic real time data fusion to render an in-focus high resolution image throughout the depth of sample in real time was implemented. 3D imaging of an African frog tadpole is demonstrated at cellular level resolution.

Citation Download Citation

Jannick P. Rolland, Panomsak Meemon, Supraja Murali, Ilhan Kaya, Nicolene Papp, Kevin P. Thompson, and Kye-Sung Lee "Gabor domain optical coherence microscopy", Proc. SPIE 7372, Optical Coherence Tomography and Coherence Techniques IV, 73721K (13 July 2009); https://doi.org/10.1117/12.831846

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