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Proceedings Article

High-sensitivity near-IR absorption measurements of nanoliter samples in a cavity enhanced fiber sensor

[+] Author Affiliations
Anthony L. Gomez, Julia A. Fruetel, Ray P. Bambha

Sandia National Labs. (USA)

Proc. SPIE 7397, Biosensing II, 739706 (August 21, 2009); doi:10.1117/12.826622
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From Conference Volume 7397

  • Biosensing II
  • Manijeh Razeghi; Hooman Mohseni
  • San Diego, CA | August 02, 2009

abstract

A compact fiber optic sensor is described using Incoherent Broad-Band Cavity Enhanced Absorption Spectroscopy for sensitive detection of nanoliter samples of aqueous chemicals and microorganisms in capillaries. Absorption was measured in a 70 μm gap, comparable to the inside diameter of a capillary used for electrophoresis, between the ends of two short segments of multimode fiber. The other ends of the fibers were optically contacted to dielectric mirrors to form an 11-cm cavity resonator. Light from a superluminescent diode (λ=1054 nm, BW=35 nm FWHM) was coupled into one end of the cavity, and transmission through the cavity was measured using a silicon photodiode. Dilute aqueous solutions of near infrared dye were used to determine the minimum detectable absorption change of 4x10-6 for 10 second integration and unity signal-to-noise ratio, which is approximately two orders of magnitude more sensitive than previously published results for systems with comparable sample path lengths.

© (2009) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Anthony L. Gomez ; Julia A. Fruetel and Ray P. Bambha
"High-sensitivity near-IR absorption measurements of nanoliter samples in a cavity enhanced fiber sensor", Proc. SPIE 7397, Biosensing II, 739706 (August 21, 2009); doi:10.1117/12.826622; http://dx.doi.org/10.1117/12.826622


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