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Proceedings Article

Monitoring of tumor treatment using the combination of near-infrared laser light and carbon nanotubes

[+] Author Affiliations
Wei Chen

South China Normal Univ. (China) and Univ. of Central Oklahoma (USA)

Feifan Zhou, Zhongmin Ou, Baoyan Wu, Sheng Song

South China Normal Univ. (China)

Proc. SPIE 7519, Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009), 75190X (October 28, 2009); doi:10.1117/12.843072
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From Conference Volume 7519

  • Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009)
  • Qingming Luo; Lihong V. Wang; Valery V. Tuchin; Pengcheng Li; Ling Fu
  • Wuhan, China | August 08, 2009

abstract

Single-walled carbon nanotubes (SWNTs) have a high optical absorbance in the near-infrared (NIR) region. In this special optical window, biological systems are known to be highly transparent. The optical properties of SWNTs provide an opportunity for selective photothermal therapy for cancer treatment. The application of single-walled carbon nanotubes (SWNTs) in the field of biomedicine is becoming an entirely new and exciting topic. Here, SWNTs are conjugated to integrin αvβ3 monoclonal antibody, which can bind specifically to the surface of the tumor markers. In vitro study revealed that SWNT-PEG-mAb presented a high targeting efficiency on integrin αvβ3-positive cells. Thus, SWNTs, combined with suitable tumor markers, can be used as novel nanomaterials for selective photothermal therapy for cancer treatment.

© (2009) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Wei Chen ; Feifan Zhou ; Zhongmin Ou ; Baoyan Wu and Sheng Song
"Monitoring of tumor treatment using the combination of near-infrared laser light and carbon nanotubes", Proc. SPIE 7519, Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009), 75190X (October 28, 2009); doi:10.1117/12.843072; http://dx.doi.org/10.1117/12.843072


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