Infrared surface plasmon resonance biosensor

Justin W. Cleary; Gautam Medhi; Robert E. Peale; Walter R. Buchwald; Oliver Edwards; Isaiah Oladeji

doi:10.1117/12.852576

23 April 2010 Infrared surface plasmon resonance biosensor

Justin W. Cleary, Gautam Medhi, Robert E. Peale, Walter R. Buchwald, Oliver Edwards, Isaiah Oladeji

Proceedings Volume 7673, Advanced Environmental, Chemical, and Biological Sensing Technologies VII; 767306 (2010) https://doi.org/10.1117/12.852576
Event: SPIE Defense, Security, and Sensing, 2010, Orlando, Florida, United States

Abstract

A Surface Plasmon Resonance (SPR) biosensor that operates deep into the infrared (3-11 μm wavelengths) is potentially capable of biomolecule recognition based both on selective binding and on characteristic vibrational modes. A goal is to operate specifically at wavelengths where biological analytes are strongly differentiated by their IR absorption spectra and where the refractive index is increased by dispersion. This will provide enhanced sensitivity and selectivity, when biological analytes bind reversibly to biomolecular recognition elements attached to the sensor surface. This paper describes work on the optical and materials aspects of IR surface plasmon resonances. First, three possible coupling schemes are considered: hemicylindrical prisms, triangular prisms, and gratings. Second, materials with plasma frequencies one order of magnitude smaller than for noble metals are considered, including doped semiconductors and semimetals.

Citation Download Citation

Justin W. Cleary, Gautam Medhi, Robert E. Peale, Walter R. Buchwald, Oliver Edwards, and Isaiah Oladeji "Infrared surface plasmon resonance biosensor", Proc. SPIE 7673, Advanced Environmental, Chemical, and Biological Sensing Technologies VII, 767306 (23 April 2010); https://doi.org/10.1117/12.852576

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