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Proceedings Article

High-sensitive blood flow imaging of the retina and choroid by using double-beam optical coherence angiography

[+] Author Affiliations
Shuichi Makita, Masahiro Yamanari, Yoshiaki Yasuno

Univ. of Tsukuba (Japan) and Computational Optics and Ophthalmology Group (Japan)

Masahiro Miura

Tokyo Medical Univ. Ibaraki Medical Ctr. (Japan) and Computational Optics and Ophthalmology Group (Japan)

Proc. SPIE 7550, Ophthalmic Technologies XX, 75500E (March 05, 2010); doi:10.1117/12.840138
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From Conference Volume 7550

  • Ophthalmic Technologies XX
  • Fabrice Manns; Per G. Söderberg; Arthur Ho
  • San Francisco, California | January 23, 2010

abstract

Wide-field and high-sensitive Doppler optical coherence angiography of the posterior human eye has been demonstrated. High-sensitive phase-resolved spectral-domain optical coherence tomography using the superluminescent diode with the central wavelength of 840 nm and bandwidth of 50 nm (FWHM) is developed. Two OCT signals with a time separation are acquired simultaneously with double sampling beams divided by using a Wollaston prism and a polarization-sensitive spectrometer consisting of two line scan cameras. The total power of two beams on the cornea is 700 μW. The line scan rate of cameras is 27 kHz and each OCT channel has the sensitivity of 93 dB. The two sampling beams are separated by approximately 162 um on the retina. The scanning of the beams is applied along the plane consisting of them. A single position on the sample is scanned twice with these two beams. High-contrast and high-sensitive phase-resolved blood flow image is obtained with these two OCT signals. Since the two signals are highly correlated, the decorrelation noise is small. In addition to that, this method does not require dense lateral sampling comparing to the lateral resolution which is demanded for previous phase-sensitive flow imaging. High-speed and high-sensitive blood flow imaging is enabled. The retinal and choroidal vasculature images with the area of 7.7 × 7.7 mm (512 × 256 axial scans) are obtained within 5 s.

© (2010) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Shuichi Makita ; Masahiro Yamanari ; Masahiro Miura and Yoshiaki Yasuno
"High-sensitive blood flow imaging of the retina and choroid by using double-beam optical coherence angiography", Proc. SPIE 7550, Ophthalmic Technologies XX, 75500E (March 05, 2010); doi:10.1117/12.840138; http://dx.doi.org/10.1117/12.840138


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