High-sensitive blood flow imaging of the retina and choroid by using double-beam optical coherence angiography

Shuichi Makita; Masahiro Yamanari; Masahiro Miura; Yoshiaki Yasuno

doi:10.1117/12.840138

5 March 2010 High-sensitive blood flow imaging of the retina and choroid by using double-beam optical coherence angiography

Shuichi Makita, Masahiro Yamanari, Masahiro Miura, Yoshiaki Yasuno

Author Affiliations +

Proceedings Volume 7550, Ophthalmic Technologies XX; 75500E (2010) https://doi.org/10.1117/12.840138
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Wide-field and high-sensitive Doppler optical coherence angiography of the posterior human eye has been demonstrated. High-sensitive phase-resolved spectral-domain optical coherence tomography using the superluminescent diode with the central wavelength of 840 nm and bandwidth of 50 nm (FWHM) is developed. Two OCT signals with a time separation are acquired simultaneously with double sampling beams divided by using a Wollaston prism and a polarization-sensitive spectrometer consisting of two line scan cameras. The total power of two beams on the cornea is 700 μW. The line scan rate of cameras is 27 kHz and each OCT channel has the sensitivity of 93 dB. The two sampling beams are separated by approximately 162 um on the retina. The scanning of the beams is applied along the plane consisting of them. A single position on the sample is scanned twice with these two beams. High-contrast and high-sensitive phase-resolved blood flow image is obtained with these two OCT signals. Since the two signals are highly correlated, the decorrelation noise is small. In addition to that, this method does not require dense lateral sampling comparing to the lateral resolution which is demanded for previous phase-sensitive flow imaging. High-speed and high-sensitive blood flow imaging is enabled. The retinal and choroidal vasculature images with the area of 7.7 × 7.7 mm (512 × 256 axial scans) are obtained within 5 s.

Citation Download Citation

Shuichi Makita, Masahiro Yamanari, Masahiro Miura, and Yoshiaki Yasuno "High-sensitive blood flow imaging of the retina and choroid by using double-beam optical coherence angiography", Proc. SPIE 7550, Ophthalmic Technologies XX, 75500E (5 March 2010); https://doi.org/10.1117/12.840138

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