Miniaturized neural interfaces and implants

Thomas Stieglitz; Tim Boretius; Juan Ordonez; Christina Hassler; Christian Henle; Wolfgang Meier; Dennis T. T. Plachta; Martin Schuettler

doi:10.1117/12.912526

14 February 2012 Miniaturized neural interfaces and implants

Thomas Stieglitz, Tim Boretius, Juan Ordonez, Christina Hassler, Christian Henle, Wolfgang Meier, Dennis T. T. Plachta, Martin Schuettler

Author Affiliations +

Proceedings Volume 8251, Microfluidics, BioMEMS, and Medical Microsystems X; 82510A (2012) https://doi.org/10.1117/12.912526
Event: SPIE MOEMS-MEMS, 2012, San Francisco, California, United States

Abstract

Neural prostheses are technical systems that interface nerves to treat the symptoms of neurological diseases and to restore sensory of motor functions of the body. Success stories have been written with the cochlear implant to restore hearing, with spinal cord stimulators to treat chronic pain as well as urge incontinence, and with deep brain stimulators in patients suffering from Parkinson's disease. Highly complex neural implants for novel medical applications can be miniaturized either by means of precision mechanics technologies using known and established materials for electrodes, cables, and hermetic packages or by applying microsystems technologies. Examples for both approaches will be introduced and discussed. Electrode arrays for recording of electrocorticograms during presurgical epilepsy diagnosis have been manufactured using approved materials and a marking laser to achieve an integration density that is adequate in the context of brain machine interfaces, e.g. on the motor cortex. Microtechnologies have to be used for further miniaturization to develop polymer-based flexible and light weighted electrode arrays to interface the peripheral and central nervous system. Polyimide as substrate and insulation material will be discussed as well as several application examples for nerve interfaces like cuffs, filament like electrodes and large arrays for subdural implantation.

Citation Download Citation

Thomas Stieglitz, Tim Boretius, Juan Ordonez, Christina Hassler, Christian Henle, Wolfgang Meier, Dennis T. T. Plachta, and Martin Schuettler "Miniaturized neural interfaces and implants", Proc. SPIE 8251, Microfluidics, BioMEMS, and Medical Microsystems X, 82510A (14 February 2012); https://doi.org/10.1117/12.912526

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