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Proceedings Article

Quantifying thermal modifications on laser welded skin tissue

[+] Author Affiliations
Hasim Ö. Tabakoglu

Fatih Univ. (Turkey)

Murat Gülsoy

Bogaziçi Univ, (Turkey)

Proc. SPIE 7902, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IX, 79020C (February 10, 2011); doi:10.1117/12.874603
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From Conference Volume 7902

  • Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IX
  • Daniel L. Farkas; Dan V. Nicolau; Robert C. Leif
  • San Francisco, California, USA | January 22, 2011

abstract

Laser tissue welding is a potential medical treatment method especially on closing cuts implemented during any kind of surgery. Photothermal effects of laser on tissue should be quantified in order to determine optimal dosimetry parameters. Polarized light and phase contrast techniques reveal information about extend of thermal change over tissue occurred during laser welding application. Change in collagen structure in skin tissue stained with hematoxilen and eosin samples can be detected. In this study, three different near infrared laser wavelengths (809 nm, 980 nm and 1070 nm) were compared for skin welding efficiency. 1 cm long cuts were treated spot by spot laser application on Wistar rats' dorsal skin, in vivo. In all laser applications, 0.5 W of optical power was delivered to the tissue, 5 s continuously, resulting in 79.61 J/cm2 energy density (15.92 W/cm2 power density) for each spot. The 1st, 4th, 7th, 14th, and 21st days of recovery period were determined as control days, and skin samples needed for histology were removed on these particular days. The stained samples were examined under a light microscope. Images were taken with a CCD camera and examined with imaging software. 809 Nm laser was found to be capable of creating strong full-thickness closure, but thermal damage was evident. The thermal damage from 980 nm laser welding was found to be more tolerable. The results showed that 1070 nm laser welding produced noticeably stronger bonds with minimal scar formation.

© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

Hasim Ö. Tabakoglu and Murat Gülsoy
"Quantifying thermal modifications on laser welded skin tissue", Proc. SPIE 7902, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IX, 79020C (February 10, 2011); doi:10.1117/12.874603; http://dx.doi.org/10.1117/12.874603


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