A pneumatic actuated microfluidic beads-trapping device

Guocheng Shao; Ziliang Cai; Jun Wang; Wanjun Wang; Yuehe Lin

doi:10.1117/12.878468

14 February 2011 A pneumatic actuated microfluidic beads-trapping device

Guocheng Shao, Ziliang Cai, Jun Wang, Wanjun Wang, Yuehe Lin

Proceedings Volume 7929, Microfluidics, BioMEMS, and Medical Microsystems IX; 792908 (2011) https://doi.org/10.1117/12.878468
Event: SPIE MOEMS-MEMS, 2011, San Francisco, California, United States

Abstract

The development of a polydimethylsiloxane (PDMS) microfluidic microbeads trapping device is reported in this paper. Besides fluid channels, the proposed device includes a pneumatic control chamber and a beads-trapping chamber with a filter array structure. The pneumatic flow control chamber and the beads-trapping chamber are vertically stacked and separated by a thin membrane. By adjusting the pressure in the pneumatic control chamber, the membrane can either be pushed against the filter array to set the device in "trapping mode" or be released to set the device in "releasing mode". In this paper, a computational fluid dynamics simulation was conducted to optimize the geometry design of the filter array structure; the device fabrication was also carried out. The prototype device was tested and the preliminary experimental results showed that it can be used as a beads-trapping unit for various biochemistry and analytical chemistry applications, especially for flow injection analysis systems.

Citation Download Citation

Guocheng Shao, Ziliang Cai, Jun Wang, Wanjun Wang, and Yuehe Lin "A pneumatic actuated microfluidic beads-trapping device", Proc. SPIE 7929, Microfluidics, BioMEMS, and Medical Microsystems IX, 792908 (14 February 2011); https://doi.org/10.1117/12.878468

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