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Proceedings Article

Single particle imaging with soft x-rays at the Linac Coherent Light Source

[+] Author Affiliations
Andrew V. Martin, Andrew Aquila, Saša Bajt, Miriam Barthelmess, Anton Barty, Nicola Coppola, Daniel P. DePonte, Holger Fleckenstein, Lars Gumprecht, Mengning Liang, Karol Nass, Joachim Schultz, Francesco Stellato, Thomas A. White

Deutsches Elektronen-Synchrotron (Germany)

Jakob Andreasson, Tomas Ekeberg, Max Hantke, Olof Jönsson, Duško Odic, Martin Svenda, Daniel Westphal, Janos Hajdu

Uppsala Univ. (Sweden)

Thomas R. M. Barends, Elisabeth Hartmann, Stephan Kassemeyer, Lukas Lomb, Robert L. Shoeman, Jan Steinbrener

Max-Planck-Institut für medizinische Forschung (Germany)

W. Henry Benner, George R. Farquar, Matthias Frank, Stephan P. Hau-Riege

Lawrence Livermore National Lab. (USA)

Christoph Bostedt, John D. Bozek, Phillip Bucksbaum, Christina Y. Hampton, Jacek Krzywinski, Ne-Te Duane Loh, Marc Messerschmidt, M. Marvin Seibert, Raymond G. Sierra, Dmitri Starodub, Garth Williams, Michael J. Bogan

SLAC National Accelerator Lab. (USA)

Carl Caleman, Henry N. Chapman

Deutsches Elektronen-Synchrotron (Germany) and Univ. of Hamburg (Germany)

Sascha W. Epp, Benjamin Erk, André Hoemke, Benedikt Rudek, Artem Rudenko, Carlo Schmidt, Joachim Ullrich

Ctr. for Free Electron Laser Science (Germany) and Max-Planck-Institut für Kernphysik (Germany)

Lutz Foucar, Faton Krasniqi, Daniel Rolles, Ilme Schlichting

Max-Planck-Institut für medizinische Forschung (Germany) and Ctr. for Free Electron Laser Science (Germany)

Andreas Hartmann, Robert Hartmann, Peter Holl, Christian Reich, Heike Soltau

PNSensor GmbH (Germany)

Günther Hauser, Nils Kimmel, Lothar Strüder, Georg Weidenspointner

Max-Planck-Institut Halbleiterlabor (Germany) and Max-Planck-Institut für extraterrestrische Physik (Germany)

Maya Kiskinova, Emanuele Pedersoli

Sincrotrone Trieste S.C.p.A. (Italy)

Filipe R. N. C. Maia, Stefano Marchesini

Lawrence Berkeley National Lab. (USA)

Herbert Tobias

Cornell Univ. (USA)

Proc. SPIE 8078, Advances in X-ray Free-Electron Lasers: Radiation Schemes, X-ray Optics, and Instrumentation, 807809 (May 20, 2011); doi:10.1117/12.886754
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From Conference Volume 8078

  • Advances in X-ray Free-Electron Lasers: Radiation Schemes, X-ray Optics, and Instrumentation
  • Thomas Tschentscher; Daniele Cocco
  • Prague, Czech Republic | April 18, 2011

abstract

Results of coherent diffractive imaging experiments performed with soft X-rays (1-2 keV) at the Linac Coherent Light Source are presented. Both organic and inorganic nano-sized objects were injected into the XFEL beam as an aerosol focused with an aerodynamic lens. The high intensity and femtosecond duration of X-ray pulses produced by the Linac Coherent Light Source allow structural information to be recorded by X-ray diffraction before the particle is destroyed. Images were formed by using iterative methods to phase single shot diffraction patterns. Strategies for improving the reconstruction methods have been developed. This technique opens up exciting opportunities for biological imaging, allowing structure determination without freezing, staining or crystallization.

© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

Andrew V. Martin ; Jakob Andreasson ; Andrew Aquila ; Saša Bajt ; Thomas R. M. Barends, et al.
"Single particle imaging with soft x-rays at the Linac Coherent Light Source", Proc. SPIE 8078, Advances in X-ray Free-Electron Lasers: Radiation Schemes, X-ray Optics, and Instrumentation, 807809 (May 20, 2011); doi:10.1117/12.886754; http://dx.doi.org/10.1117/12.886754


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