Novel instrumentation of multispectral imaging technology for detecting tissue abnormity

Dingrong Yi; Linghua Kong

doi:10.1117/12.929398

15 October 2012 Novel instrumentation of multispectral imaging technology for detecting tissue abnormity

Dingrong Yi, Linghua Kong

Proceedings Volume 8498, Optics and Photonics for Information Processing VI; 84980J (2012) https://doi.org/10.1117/12.929398
Event: SPIE Optical Engineering + Applications, 2012, San Diego, California, United States

Abstract

Multispectral imaging is becoming a powerful tool in a wide range of biological and clinical studies by adding spectral, spatial and temporal dimensions to visualize tissue abnormity and the underlying biological processes. A conventional spectral imaging system includes two physically separated major components: a band-passing selection device (such as liquid crystal tunable filter and diffraction grating) and a scientific-grade monochromatic camera, and is expensive and bulky. Recently micro-arrayed narrow-band optical mosaic filter was invented and successfully fabricated to reduce the size and cost of multispectral imaging devices in order to meet the clinical requirement for medical diagnostic imaging applications. However the challenging issue of how to integrate and place the micro filter mosaic chip to the targeting focal plane, i.e., the imaging sensor, of an off-shelf CMOS/CCD camera is not reported anywhere. This paper presents the methods and results of integrating such a miniaturized filter with off-shelf CMOS imaging sensors to produce handheld real-time multispectral imaging devices for the application of early stage pressure ulcer (ESPU) detection. Unlike conventional multispectral imaging devices which are bulky and expensive, the resulting handheld real-time multispectral ESPU detector can produce multiple images at different center wavelengths with a single shot, therefore eliminates the image registration procedure required by traditional multispectral imaging technologies.

Citation Download Citation

Dingrong Yi and Linghua Kong "Novel instrumentation of multispectral imaging technology for detecting tissue abnormity", Proc. SPIE 8498, Optics and Photonics for Information Processing VI, 84980J (15 October 2012); https://doi.org/10.1117/12.929398

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