Breast density is known as a strong risk factor for breast cancer. Clinical assessment of breast density during screening
mammography is often done by radiologists through visual evaluation or by a computer program. Automated computer
methods offer the potential for non-subjective density assessments. With the rapid development and increased utilization
of tomosynthesis clinically, there is a practical need for systems to provide automated breast density measurements in
tomosynthesis like those available in mammography.
QuantraTM is a software package using physical modeling of mammography systems, and performs volumetric
assessment of breast tissue composition for conventional mammography. In this paper, we describe recent developments
to extend Quantra to calculate breast density using tomosynthesis projection images. Our development took advantage of
the combo imaging mode of Hologic Selenia DimensionsTM system, which allowed co-registered conventional 2D
mammogram and 3D tomosynthesis images to be acquired in a single compression. We used the Quantra results of 2D
mammograms as a reference to refine the new processing algorithm for tomosynthesis images. This paper describes
details of the new algorithm and provides some preliminary results.© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Baorui Ren ; Andrew Smith and Zhenxue Jing
"Measurement of breast density with digital breast tomosynthesis", Proc. SPIE 8313, Medical Imaging 2012: Physics of Medical Imaging, 83134Q (February 23, 2012); doi:10.1117/12.913357; http://dx.doi.org/10.1117/12.913357