0

Full Content is available to subscribers

Subscribe/Learn More  >
Proceedings Article

Multiview hyperspectral topography of tissue structural and functional characteristics

[+] Author Affiliations
Shiwu Zhang, Peng Liu, Ronald Xu

Univ. of Science and Technology of China (China)

Jiwei Huang

The Ohio State Univ. (United States)

Proc. SPIE 8553, Optics in Health Care and Biomedical Optics V, 85530P (December 11, 2012); doi:10.1117/12.1000006
Text Size: A A A
From Conference Volume 8553

  • Optics in Health Care and Biomedical Optics V
  • Qingming Luo; Ying Gu; Xingde D. Li
  • Beijing, China | November 05, 2012

abstract

Accurate and in vivo characterization of structural, functional, and molecular characteristics of biological tissue will facilitate quantitative diagnosis, therapeutic guidance, and outcome assessment in many clinical applications, such as wound healing, cancer surgery, and organ transplantation. However, many clinical imaging systems have limitations and fail to provide noninvasive, real time, and quantitative assessment of biological tissue in an operation room. To overcome these limitations, we developed and tested a multiview hyperspectral imaging system. The multiview hyperspectral imaging system integrated the multiview and the hyperspectral imaging techniques in a single portable unit. Four plane mirrors are cohered together as a multiview reflective mirror set with a rectangular cross section. The multiview reflective mirror set was placed between a hyperspectral camera and the measured biological tissue. For a single image acquisition task, a hyperspectral data cube with five views was obtained. The five-view hyperspectral image consisted of a main objective image and four reflective images. Three-dimensional topography of the scene was achieved by correlating the matching pixels between the objective image and the reflective images. Three-dimensional mapping of tissue oxygenation was achieved using a hyperspectral oxygenation algorithm. The multiview hyperspectral imaging technique is currently under quantitative validation in a wound model, a tissue-simulating blood phantom, and an in vivo biological tissue model. The preliminary results have demonstrated the technical feasibility of using multiview hyperspectral imaging for three-dimensional topography of tissue functional properties.© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

Shiwu Zhang ; Peng Liu ; Jiwei Huang and Ronald Xu
"Multiview hyperspectral topography of tissue structural and functional characteristics", Proc. SPIE 8553, Optics in Health Care and Biomedical Optics V, 85530P (December 11, 2012); doi:10.1117/12.1000006; http://dx.doi.org/10.1117/12.1000006


Access This Article
Sign In to Access Full Content
Please Wait... Processing your request... Please Wait.
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
 

Figures

Tables

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement

Buy this article ($18 for members, $25 for non-members).
Sign In