Tissue regeneration with photobiomodulation

Elieza G. Tang; Praveen R. Arany

doi:10.1117/12.2019284

8 March 2013 Tissue regeneration with photobiomodulation

Elieza G. Tang, Praveen R. Arany

Proceedings Volume 8569, Mechanisms for Low-Light Therapy VIII; 856907 (2013) https://doi.org/10.1117/12.2019284
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Low level light therapy (LLLT) has been widely reported to reduce pain and inflammation and enhance wound healing and tissue regeneration in various settings. LLLT has been noted to have both stimulatory and inhibitory biological effects and these effects have been termed Photobiomodulation (PBM). Several elegant studies have shown the key role of Cytochrome C oxidase and ROS in initiating this process. The downstream biological responses remain to be clearly elucidated. Our work has demonstrated activation of an endogenous latent growth factor complex, TGF-β1, as one of the major biological events in PBM. TGF-β1 has critical roles in various biological processes especially in inflammation, immune responses, wound healing and stem cell biology. This paper overviews some of the studies demonstrating the efficacy of PBM in promoting tissue regeneration.

Citation Download Citation

Elieza G. Tang and Praveen R. Arany "Tissue regeneration with photobiomodulation", Proc. SPIE 8569, Mechanisms for Low-Light Therapy VIII, 856907 (8 March 2013); https://doi.org/10.1117/12.2019284

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