Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation

Andrey V. Dunaev; Victor V. Sidorov; Neil A. Stewart; Sergei G. Sokolovski; Edik U. Rafailov

doi:10.1117/12.2001797

22 March 2013 Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation

Andrey V. Dunaev, Victor V. Sidorov, Neil A. Stewart, Sergei G. Sokolovski, Edik U. Rafailov

Author Affiliations +

Proceedings Volume 8572, Advanced Biomedical and Clinical Diagnostic Systems XI; 857205 (2013) https://doi.org/10.1117/12.2001797
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

The integration of multiple optical techniques within a single diagnostic device is used to address the difficulties in standardising measurement of cutaneous blood micro-dynamics caused by high variability. We demonstrate the benefits of simultaneous assessment of blood relative volume (V_b), microcirculation index (I_m) and tissue oxygen saturation (S_tO₂), during long-term examination of healthy volunteers. Consequently, five rhythmic components: endothelial, neurogenic, myogenic, breath and heart pulses were established showing high variability up to 30 – 50% as well as in initial parameters around 16%. All rhythmic components were synchronous with some latency between I_m and S_tO₂ in the myogenic component supports the hypothesis of strong correlation between peripheral hemodynamics and oxygen utilisation in tissues.

Citation Download Citation

Andrey V. Dunaev, Victor V. Sidorov, Neil A. Stewart, Sergei G. Sokolovski, and Edik U. Rafailov "Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation", Proc. SPIE 8572, Advanced Biomedical and Clinical Diagnostic Systems XI, 857205 (22 March 2013); https://doi.org/10.1117/12.2001797

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