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Proceedings Article

Sound speed based patient-specific biomechanical modeling for registration of USCT volumes with X-ray mammograms

[+] Author Affiliations
T. Hopp, A. Stromboni, M. Zapf, H. Gemmeke, N. V. Ruiter

Karlsruher Institut für Technologie (Germany)

N. Duric

Karmanos Cancer Institute (United States)

Proc. SPIE 8675, Medical Imaging 2013: Ultrasonic Imaging, Tomography, and Therapy, 86750L (March 29, 2013); doi:10.1117/12.2006726
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From Conference Volume 8675

  • Medical Imaging 2013: Ultrasonic Imaging, Tomography, and Therapy
  • Johan G. Bosch; Marvin M. Doyley
  • Lake Buena Vista (Orlando Area), Florida, USA | February 09, 2013

abstract

Ultrasound Computer Tomography is an upcoming imaging modality for early breast cancer detection. For evaluation of the method, comparison with the standard method X-ray mammography is of strongest interest. To overcome the significant differences in dimensionality and compression state of the breast, in earlier work a registration method based on biomechanical modeling of the breast was proposed. However only homogeneous models could be applied, i.e. inner structures of the breast were neglected. In this work we extend the biomechanical modeling of the breast by estimating patient-specific tissue parameters automatically from the speed of sound volume. Two heterogeneous models are proposed modeling a quadratic and an exponential relationship between speed of sound and tissue stiffness. The models were evaluated using phantom images and clinical data. The size of all lesions is better preserved using heterogeneous models, especially using an exponential relationship. The presented approach yields promising results and gives a physical justification to our registration method. It can be considered as a first step towards a realistic modeling of the breast. © (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

T. Hopp ; A. Stromboni ; N. Duric ; M. Zapf ; H. Gemmeke, et al.
" Sound speed based patient-specific biomechanical modeling for registration of USCT volumes with X-ray mammograms ", Proc. SPIE 8675, Medical Imaging 2013: Ultrasonic Imaging, Tomography, and Therapy, 86750L (March 29, 2013); doi:10.1117/12.2006726; http://dx.doi.org/10.1117/12.2006726


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