Microscopy with multimode fibers

Christophe Moser; Ioannis Papadopoulos; Salma Farahi; Demetri Psaltis

doi:10.1117/12.2021563

23 May 2013 Microscopy with multimode fibers

Christophe Moser, Ioannis Papadopoulos, Salma Farahi, Demetri Psaltis

Proceedings Volume 8792, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials; 879219 (2013) https://doi.org/10.1117/12.2021563
Event: SPIE Optical Metrology 2013, 2013, Munich, Germany

Abstract

Microscopes are usually thought of comprising imaging elements such as objectives and eye-piece lenses. A different type of microscope, used for endoscopy, consists of waveguiding elements such as fiber bundles, where each fiber in the bundle transports the light corresponding to one pixel in the image. Recently a new type of microscope has emerged that exploits the large number of propagating modes in a single multimode fiber. We have successfully produced fluorescence images of neural cells with sub-micrometer resolution via a 200 micrometer core multimode fiber. The method for achieving imaging consists of using digital phase conjugation to reproduce a focal spot at the tip of the multimode fiber. The image is formed by scanning the focal spot digitally and collecting the fluorescence point by point.

Citation Download Citation

Christophe Moser, Ioannis Papadopoulos, Salma Farahi, and Demetri Psaltis "Microscopy with multimode fibers ", Proc. SPIE 8792, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials, 879219 (23 May 2013); https://doi.org/10.1117/12.2021563

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