Quantification of inflammation in colonic tissue sections and wound healing in-vitro with digital holographic microscopy

Dominik Bettenworth; Philipp Lenz; Philipp Krausewitz; Markus Brückner; Steffi Ketelhut; Gert von Bally; Dirk Domagk; Björn Kemper

doi:10.1117/12.2032501

17 June 2013 Quantification of inflammation in colonic tissue sections and wound healing in-vitro with digital holographic microscopy

Dominik Bettenworth, Philipp Lenz, Philipp Krausewitz, Markus Brückner, Steffi Ketelhut, Gert von Bally, Dirk Domagk, Björn Kemper

Author Affiliations +

Proceedings Volume 8797, Advanced Microscopy Techniques III; 879702 (2013) https://doi.org/10.1117/12.2032501
Event: European Conferences on Biomedical Optics, 2013, Munich, Germany

Abstract

We show that the tissue refractive index, obtained from quantitative digital holographic microscopy (DHM) phase contrast images of unstained histological colonic sections, is directly related to the degree of inflammation in experimental colitis. In addition, it is demonstrated that quantitative DHM phase contrast is capable to quantify in-vitro wound healing assays.

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Dominik Bettenworth, Philipp Lenz, Philipp Krausewitz, Markus Brückner, Steffi Ketelhut, Gert von Bally, Dirk Domagk, and Björn Kemper "Quantification of inflammation in colonic tissue sections and wound healing in-vitro with digital holographic microscopy", Proc. SPIE 8797, Advanced Microscopy Techniques III, 879702 (17 June 2013); https://doi.org/10.1117/12.2032501

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