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Proceedings Article

The DNA assembler for next generation sequencers

[+] Author Affiliations
Jan Twardowski, Robert Nowak

Warsaw Univ. of Technology (Poland)

Proc. SPIE 8903, Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2013, 890317 (October 25, 2013); doi:10.1117/12.2032637
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From Conference Volume 8903

  • Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2013
  • Ryszard S. Romaniuk
  • Wilga, Poland | May 27, 2013

abstract

The aim of this paper is new application for de novo assembly DNA reads produced by next generation sequencers. The algorithm based on de Bruin graph is proposed, it uses both DNA strands: coding and complementary. The read errors are corrected. The repetitive sequences longer than read are correctly reconstructed in some cases. The application in client-server architecture was developed and tested on pseudo-random sequences and reads generated from genomes of model organisms. © (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

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Jan Twardowski and Robert Nowak
" The DNA assembler for next generation sequencers ", Proc. SPIE 8903, Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2013, 890317 (October 25, 2013); doi:10.1117/12.2032637; http://dx.doi.org/10.1117/12.2032637


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