Small angle scattering polarization biopsy: a comparative analysis of various skin diseases

D. A. Zimnyakov; M. V. Alonova; S. B. Yermolenko; P. V. Ivashko; E. M. Reshetnikova; E. M. Galkina; S. R. Utz

doi:10.1117/12.2053235

17 December 2013 Small angle scattering polarization biopsy: a comparative analysis of various skin diseases

D. A. Zimnyakov, M. V. Alonova, S. B. Yermolenko, P. V. Ivashko, E. M. Reshetnikova, E. M. Galkina, S. R. Utz

Proceedings Volume 9066, Eleventh International Conference on Correlation Optics; 90661N (2013) https://doi.org/10.1117/12.2053235
Event: Eleventh International Conference on Correlation Optics, 2013, Chernivsti, Ukraine

Abstract

An approach to differentiation of the morphological features of normal and pathological human epidermis on the base of statistical analysis of the local polarization states of laser light forward scattered by in-vitro tissue samples is discussed. The eccentricity and the azimuth angle of local polarization ellipses retrieved for various positions of the focused laser beam on the tissue surface, and the coefficient of collimated transmittance are considered as the diagnostic parameters for differentiation. The experimental data obtained with the psoriasis, discoid lupus erythematosus, alopecia, lichen planus, scabies, demodex, and normal skin samples are presented.

Citation Download Citation

D. A. Zimnyakov, M. V. Alonova, S. B. Yermolenko, P. V. Ivashko, E. M. Reshetnikova, E. M. Galkina, and S. R. Utz "Small angle scattering polarization biopsy: a comparative analysis of various skin diseases", Proc. SPIE 9066, Eleventh International Conference on Correlation Optics, 90661N (17 December 2013); https://doi.org/10.1117/12.2053235

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available