Reflectance confocal microscopy of oral epithelial tissue using an electrically tunable lens

Joey M. Jabbour; Bilal H. Malik; Rodrigo Cuenca; Shuna Cheng; Javier A. Jo; Yi-Shing L. Cheng; John M. Wright; Kristen C. Maitland

doi:10.1117/12.2037046

27 February 2014 Reflectance confocal microscopy of oral epithelial tissue using an electrically tunable lens

Joey M. Jabbour, Bilal H. Malik, Rodrigo Cuenca, Shuna Cheng, Javier A. Jo, Yi-Shing L. Cheng, John M. Wright, Kristen C. Maitland

Author Affiliations +

Proceedings Volume 8935, Advanced Biomedical and Clinical Diagnostic Systems XII; 89350R (2014) https://doi.org/10.1117/12.2037046
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

We present the use of a commercially available electrically tunable lens to achieve axial scanning in a reflectance confocal microscope. Over a 255 μm axial scan range, the lateral and axial resolutions varied from 1-2 μm and 4-14 μm, respectively, dependent on the variable focal length of the tunable lens. Confocal imaging was performed on normal human biopsies from the oral cavity ex vivo. Sub-cellular morphologic features were seen throughout the depth of the epithelium while axially scanning using the focus tunable lens.

Citation Download Citation

Joey M. Jabbour, Bilal H. Malik, Rodrigo Cuenca, Shuna Cheng, Javier A. Jo, Yi-Shing L. Cheng, John M. Wright, and Kristen C. Maitland "Reflectance confocal microscopy of oral epithelial tissue using an electrically tunable lens", Proc. SPIE 8935, Advanced Biomedical and Clinical Diagnostic Systems XII, 89350R (27 February 2014); https://doi.org/10.1117/12.2037046

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