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Proceedings Article

Celiac disease biodetection using lossy-mode resonances generated in tapered single-mode optical fibers

[+] Author Affiliations
A. B. Socorro, J. M. Corres, I. Del Villar, I. R. Matias, F. J. Arregui

Univ. Pública de Navarra (Spain)

Proc. SPIE 9157, 23rd International Conference on Optical Fibre Sensors, 91573J (June 2, 2014); doi:10.1117/12.2059254
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From Conference Volume 9157

  • 23rd International Conference on Optical Fibre Sensors
  • José M. López-Higuera; Julian D. C. Jones; Manuel López-Amo; José L. Santos
  • Santander, Spain | June 02, 2014

abstract

This work presents the development and test of an anti-gliadin antibodies biosensor based on lossy mode resonances (LMRs) to detect celiac disease. Several polyelectrolites were used to perform layer-by-layer assembly processes in order to generate the LMR and to fabricate a gliadin-embedded thin-film. The LMR shifted 20 nm when immersed in a 5 ppm anti-gliadin antibodies-PBS solution, what makes this bioprobe suitable for detecting celiac disease. This is the first time, to our knowledge, that LMRs are used to detect celiac disease and these results suppose promising prospects on the use of such phenomena as biological detectors. © (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

A. B. Socorro ; J. M. Corres ; I. Del Villar ; I. R. Matias and F. J. Arregui
" Celiac disease biodetection using lossy-mode resonances generated in tapered single-mode optical fibers ", Proc. SPIE 9157, 23rd International Conference on Optical Fibre Sensors, 91573J (June 2, 2014); doi:10.1117/12.2059254; http://dx.doi.org/10.1117/12.2059254


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