Novel 3D plasmonic nano-electrodes for cellular investigations and neural interfaces

Mario Malerba; Michele Dipalo; Gabriele C. Messina; Hayder Amin; Rosanna La Rocca; Victoria Shalabaeva; Alessandro Simi; Alessandro Maccione; Luca Berdondini; Francesco De Angelis

doi:10.1117/12.2066274

27 August 2014 Novel 3D plasmonic nano-electrodes for cellular investigations and neural interfaces

Mario Malerba, Michele Dipalo, Gabriele C. Messina, Hayder Amin, Rosanna La Rocca, Victoria Shalabaeva, Alessandro Simi, Alessandro Maccione, Luca Berdondini, Francesco De Angelis

Author Affiliations +

Proceedings Volume 9166, Biosensing and Nanomedicine VII; 91660N (2014) https://doi.org/10.1117/12.2066274
Event: SPIE NanoScience + Engineering, 2014, San Diego, California, United States

Abstract

We propose the development of an innovative plasmonic-electronic multifunctional platform, capable at the same time of performing chemical analysis and electronic recordings from a cellular interface. The system, based on 3D hollow metallic nanotubes, integrated on customized multi-electrode-arrays, allows the study of neuronal signaling over different lengths, spanning from the molecular, to the cellular, to the network scale. Here we show that the same structures are efficient electric field enhancers, despite the continuous metal layer at the base, which connects them to the electric components of the integrated circuits. The methodology we propose, due to its simplicity and high throughput, has the potential for further improvements both in the field of plasmonics, and in the integration on large areas of commercial active electronic devices.

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Mario Malerba, Michele Dipalo, Gabriele C. Messina, Hayder Amin, Rosanna La Rocca, Victoria Shalabaeva, Alessandro Simi, Alessandro Maccione, Luca Berdondini, and Francesco De Angelis "Novel 3D plasmonic nano-electrodes for cellular investigations and neural interfaces", Proc. SPIE 9166, Biosensing and Nanomedicine VII, 91660N (27 August 2014); https://doi.org/10.1117/12.2066274

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